SubtiBank SubtiBank
Version comparison:

2019-10-08 09:50:272019-10-08 09:37:40

The protein

Catalyzed reaction/ biological activity

α-D-glucose 1-phosphate --> α-D-glucose 6-phosphate (according to UniProt)

D-glucosamine 6-phosphate --> α-D-glucosamine 1-phosphate (secondary activity, this activity is increased by a G47S mutation) [pubmed|31589605]

α-D-glucose 1-phosphate --> α-D-glucose 6-phosphate (according to UniProt)

D-glucosamine 6-phosphate --> α-D-glucosamine 1-phosphate (secondary activity) [pubmed|31589605]

The protein

Additional information

PgcA inhibits [[protein|FtsZ]] ring assembly (indirect effect due to a defect in UDP-glucose synthesis)[Pubmed|17662947]

a PgcA (G47S) variant suppresses the growth defect of a glmR mutant on gluconeogenic carbon sources in the absence of glucose due to the increased phosphoglucosamine mutase activity [pubmed|31589605]

PgcA inhibits [[protein|FtsZ]] ring assembly (indirect effect due to a defect in UDP-glucose synthesis)[Pubmed|17662947]